求大神帮忙看看,以下问题该怎么解决!!!万分感谢

[ERROR]2014-11-2822:56:23-Prototype(org.logicalcobwebs.proxool.zxm10_his[Prototyper:2... [ERROR] 2014-11-28 22:56:23-Prototype (org.logicalcobwebs.proxool.zxm10_his [Prototyper:28750])
com.microsoft.sqlserver.jdbc.SQLServerException: 到主机 的 TCP/IP 连接失败。 java.net.ConnectException: Connection refused: connect
at com.microsoft.sqlserver.jdbc.SQLServerException.makeFromDriverError(Unknown Source)
at com.microsoft.sqlserver.jdbc.SQLServerConnection.connectHelper(Unknown Source)
at com.microsoft.sqlserver.jdbc.SQLServerConnection.loginWithoutFailover(Unknown Source)
at com.microsoft.sqlserver.jdbc.SQLServerConnection.connect(Unknown Source)
at com.microsoft.sqlserver.jdbc.SQLServerDriver.connect(Unknown Source)
at java.sql.DriverManager.getConnection(Unknown Source)
at java.sql.DriverManager.getConnection(Unknown Source)
at org.logicalcobwebs.proxool.DefaultConnectionBuilder.buildConnection(DefaultConnectionBuilder.java:39)
at org.logicalcobwebs.proxool.Prototyper.buildConnection(Prototyper.java:159)
at org.logicalcobwebs.proxool.Prototyper.sweep(Prototyper.java:102)
at org.logicalcobwebs.proxool.PrototyperThread.run(PrototyperThread.java:44)
[INFO] 2014-11-28 22:56:23-Shutting down 'zxm10_his' pool immediately [Shutdown Hook] (org.logicalcobwebs.proxool.zxm10_his [Shutdown Hook:28750])
[INFO] 2014-11-28 22:56:23-Stopping Prototyper thread (org.logicalcobwebs.proxool.PrototyperController [Shutdown Hook:28750])
[INFO] 2014-11-28 22:56:23-Stopping HouseKeeper thread (org.logicalcobwebs.proxool.HouseKeeperController [Shutdown Hook:28750])
[INFO] 2014-11-28 22:59:36-Module: Alarm Box Module is not opened!! (com.ztenv.usms.ModuleRun [WrapperSimpleAppMain:0])
[INFO] 2014-11-28 22:59:37-Module: AlarmEmail server is not opened!! (com.ztenv.usms.ModuleRun [WrapperSimpleAppMain:109])
[INFO] 2014-11-28 22:59:37-Module: Sms Alarm Module is not opened!! (com.ztenv.usms.ModuleRun [WrapperSimpleAppMain:172])
[INFO] 2014-11-28 22:59:37-Initial redis client...127.0.0.1:6379 (com.ztenv.redis.RedisClient [WrapperSimpleAppMain:531])
[INFO] 2014-11-28 22:59:37-Begin to Start USMS System...... (com.ztenv.usms.server.ServerRun [WrapperSimpleAppMain:813])
[INFO] 2014-11-28 22:59:37-Begin to Initialize Service Layer...... (com.ztenv.usms.UsmsManager [WrapperSimpleAppMain:969])
[INFO] 2014-11-28 22:59:37-Initializing Database Connection...... (com.ztenv.db.DataBase [WrapperSimpleAppMain:984])
[INFO] 2014-11-28 22:59:37-Loading zxm10_cfg...... (com.ztenv.db.DataBase [WrapperSimpleAppMain:1000])
[WARN] 2014-11-28 22:59:38-No configuration found. Configuring ehcache from ehcache-failsafe.xml found in the classpath: jar:file:/C:/ZTE%20E_guard/USMS/CoreService/app/UsmsServer/scop.bem.jar!/ehcache-failsafe.xml (net.sf.ehcache.config.ConfigurationFactory [WrapperSimpleAppMain:1234])
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