Question

If we work with a strong will ,we can overcome them _______great difficultie

大家帮忙解决一下。空格选填whatever ; however ;no matter how ;which 在此先谢过啦

Answer 1

however ，no matter how 都可以。
讲解：however作连接副词时，与no matter how相当，后接形容词或副词，意为“无论……”“不管……”
句型：“however＋形容词或副词＋主语＋谓语”，这里省略了谓语are。

还有，我觉得你题目是不是少了一个定冠词the，完整的句子应该是：
If we work with a strong will ,we can overcome them however （no matter how）great the difficulties (are).

Answer 2

however

如果我们有坚定的意志，不管多难，我们都能克服。

Answer 3

however