Question

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Both drugs induce degradation of the PML/RARa oncoprotein but through different mechanisms involving distinct residues of the PML (ATO) and RARa (ATRA
and ATO)。其中开头的both drugs 指的是ATOh和ATRA。

Answer 1

这两种药物引起的PML / RARa癌蛋白，而是通过涉及的PML（三氧化二砷）和RARa（全反式维甲酸和三氧化二砷）不同的残留降解不同的机制