Question

中译英 帮忙翻译一下~谢谢啦！！

除此之外，本实验还表明补骨脂中的有效成分可以抑制炎性因子NO的释放，这与已报道的结果相一致。这种效应可以很好的降低自由基的产生诱导的炎性因子对细胞造成的损伤，这也可能是补骨脂各化合物对A549的抑制率并不是很高的原因之一。另外，NO的释放总是在H2O2升高的时间段升高，在升高后又迅速下降回归正常值，这可能说明NO处在反应链的下游阶段，它的释放与H2O2的产生是相关的，这与氧化应激反应很相似，因此可以通过氧化应激反应的特点来研究补骨脂的抗癌机理。此外，NO虽然是典型的炎性因子，但它同时也是细胞中重要的信号分子，NO的过低表达是否也可引起癌细胞死亡目前尚不清楚。
通过对比可以看出，补骨脂定和补骨脂酚，以及补骨脂素和异补骨脂素在细胞增殖、H2O2的产生和NO的释放上分别表现出了相似的规律，这可能说明这两对化合物对于A549的作用机制是相似的，而这两对之间则存在较大的差异，今后可以分别进行机理研究。此外，本研究实验结果显示，随着剂量的增大，或者随着时间的推移，补骨脂酚都会使本研究中检测的指标都逐渐向正常状态下的细胞水平靠近，这其中的机理有待进一步的研究。

Answer 1

在有道上翻译的，应该不会错In addition, this study also showed that the active ingredient can be psoralen inhibited inflammatory cytokine release of NO, which is consistent with the results reported. This effect can be very good to reduce the production of free radicals induced by inflammatory factors cause cell damage, which may be psoralen inhibition of the compounds on the A549 one of the reasons the rate is not very high. In addition, NO release is always time in the elevated H2O2 increased, then decreased rapidly in the higher return to normal, which may explain the chain reaction of NO in the downstream stages of its release and H2O2 generation is related , which is very similar to oxidative stress, it can be characterized by oxidative stress to study the anti-cancer mechanism of psoralen. In addition, NO, although typical of inflammatory factors, but it is also an important cell signaling molecule, NO is the low expression may also cause cell death is unclear.
It can be seen by comparing, psoralen and psoralen given phenol, and psoralen and psoralen in cell proliferation, H2O2 generation and the release of NO, respectively, showed a similar law, which may explain these two compounds on the A549 on the mechanism of action is similar, but the two of you there is a big difference between the future can separate mechanism. In addition, the study results show that as the dose increases, or as time goes on, bakuchiol will enable the study to detect indicators are gradually to normal state near the cellular level, the mechanism of which remains to be further study.

Answer 2

In addition, this experiment has also shown that effective constituents of Psoralea can inhibit the release of inflammatory factor-NO, this is consistent with results that have been reported. This effect may very well reduce the generation of free radicals induced by inflammatory factors causing damage to cells, it may also be the psoralen compound on A549 inhibition rate of one of the reasons is not very high. In addition, NO release is always elevated the H2O2 rise time period, after rising rapidly to decline return to normal, this may indicate NO at the downstream stages of the chain reaction, it is related to the release and production of H2O2, and oxidative stress responses are similar, so you can study on oxidation characteristics of stress response to anticancer mechanism of psoralen. In addition, although NO is typical of inflammatory factor, but it is also important in cell signaling molecules, NO expression is also too low to cause cancer cell death is not known.
Through contrast can see, Supplement bone fat will and supplement bone fat phenol, and supplement bone fat pigment and different supplement bone fat pigment in cell proliferation, and H2O2 of produced and NO of release Shang respectively performance out has similar of law, this may description this two on compounds for A549 of role mechanism is similar of, and this two on Zhijian is exists larger of differences, future can respectively for mechanism research. In addition, the study results showed, as the dose increases, or, over time, psoralen indicator for detection of phenol makes this research are gradually to be near normal state of the cell, pending further study of the mechanism for this.

Answer 3

In addition, this study also showed that the active ingredient can be psoralen inhibited inflammatory cytokine release of NO, which is consistent with the results reported. This effect can be very good to reduce the production of free radicals induced by inflammatory factors cause cell damage, which may be psoralen inhibition of the compounds on the A549 one of the reasons the rate is not very high. In addition, NO release is always time in the elevated H2O2 increased, then decreased rapidly in the higher return to normal, which may explain the chain reaction of NO in the downstream stages of its release and H2O2 generation is related , which is very similar to oxidative stress, it can be characterized by oxidative stress to study the anti-cancer mechanism of psoralen. In addition, NO, although typical of inflammatory factors, but it is also an important cell signaling molecule, NO is the low expression may also cause cell death is unclear.
It can be seen by comparing, psoralen and psoralen given phenol, and psoralen and psoralen in cell proliferation, H2O2 generation and the release of NO, respectively, showed a similar law, which may explain these two compounds on the A549 on the mechanism of action is similar, but the two of you there is a big difference between the future can separate mechanism. In addition, the study results show that as the dose increases, or as time goes on, bakuchiol will enable the study to detect indicators are gradually to normal state near the cellular level, the mechanism of which remains to be further study.

Answer 4

In addition, this experiment showed that the effective ingredient psoralea corylifolia can inhibit the release of inflammatory factor NO, this and has reported results are in agreement. This effect can be very good reduce the radicals have induced inflammatory factor of the damage to cells, it could also be psoralea corylifolia each A549 compounds to the inhibition rate and one of the reasons is not very high. In addition, NO release is always in the time period, increase H2O2 rise on the rise and drop quickly return to normal after, that could mean NO chain reaction in the downstream side of the stage, the release of it with H2O2 is generated from the related, the oxidative stress reaction with very similar, and it can be through the oxidative stress reaction to study the characteristics of psoralea corylifolia anti-cancer mechanism. In addition, NO although is typical of inflammatory factor, but it is also an important signal molecules in cell, NO low of expression is also can cause cancer cell death is not clear.

Through the contrast can see, psoralea corylifolia and psoralea corylifolia phenol, and psoralea corylifolia element and different psoralea corylifolia element in the cell proliferation and H2O2 generation and NO separately on the release of the show similar laws, and this may suggest that the two compounds for the mechanism of action of A549 is similar, and these two to exists obvious difference, respectively in the future can mechanism research. In addition, the research results show that with the increase of the dose, or with the passage of time, psoralea corylifolia phenol can make this study testing index gradually to the normal cellular level, including the mechanism of close to further research.