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ChangesinthePeripheralConcentrationsofInhibin,Follicle-StimulatingHormone,Luteinizing... Changes in the Peripheral Concentrations of Inhibin, Follicle-Stimulating Hormone, Luteinizing Hormone, Progesterone and Estradiol-17β During Turnover of Cystic Follicles in Dairy Cows with Spontaneous Follicular Cysts
Kazuhiro KENGAKU1)2)3), Tomomi TANAKA1)3) and Hideo KAMOMAE1)3)
1) Department of Veterinary Medicine, Tokyo University of Agriculture and Technology
2) Seibu Clinical Center, Chiba Prefectural Federation of Agricultural Mutual Aid Associations
3) United Graduated School of Veterinary Sciences, Gifu University
Abstract. Several studies have clarified that the follicular cysts degenerate and are replaced by newly growing follicles that develop into new follicular cysts without ovulation, i.e., turnover of ovarian follicular cysts in cows. However, the relativity of endocrinological changes, including the inhibin profile during turnover of spontaneous follicular cysts in dairy cows, is still unclear. In the present study, the relationship between turnover of follicular cysts and changes in the peripheral blood concentrations of progesterone (P), estradiol-17β (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH) and inhibin were examined in lactating dairy cows. Five cows diagnosed with follicular cysts (follicles of more than 25 mm in diameter in the absence of a corpus luteum) were investigated. Their ovarian dynamics were monitored using ultrasonography, and blood samples were collected at 2- or 3- day intervals throughout the experiment. The day when a follicle fated to become a follicular cyst reached more than 8 mm in diameter was defined as the start of a cystic follicular wave. Four of the 5 cows exhibited a similar patterns of cystic follicular changes and hormone profiles. The data from the 4 cows was used for analysis of the relationships between turnover of cystic follicles and the hormone profiles. Two or three new cystic follicular waves occurred in each cow during the experimental period. The mean diameter of the cystic follicles was more than 25 mm 13 to 15 days after the start of the cystic follicular wave, and it began to decrease 1 to 6 days before the start of the subsequent cystic follicular wave. The levels of E2 and inhibin tended to decrease for 7 to 9 days before the start of a new cystic follicular wave and to increase concomitantly with new follicular cyst growth. The levels of FSH rose for 1 to 3 days before the start of a new cystic follicular wave. The present study clarified the relationship between FSH and inhibin during turnover of spontaneous follicular cysts in dairy cows and found that it was very similar to previous results for cows. The present results suggest that an increase in FSH secretion following a reduction in inhibin secretion triggers turnover of cystic follicles in cows with spontaneous follicular cysts.
Keywords: Dairy cow, Estradiol-17β (E2), Follicular cyst, Follicle stimulating hormone (FSH), Inhibin
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变化,在周围的浓度抑制素,卵泡刺激素,促黄体生成激素,孕酮和雌激素- 17 β期间营业额的囊性卵泡,在奶牛自发性滤泡囊肿
球员kazuhiro kengaku1 ) 2 ) 3 ) , tomomi tanaka1 ) 3 )和秀郎kamomae1 ) 3 )
1 )部门的兽医药品,东京大学农业和科技
2 )西武临床中心,千叶县工商联农业互助协会
3 )美国学校毕业的兽医学,岐阜大学
抽象的。几项研究已经澄清说,滤泡囊肿堕落,并更换了新人成长卵泡即发展成新的滤泡囊肿无排卵,即营业额的卵巢滤泡囊肿的奶牛。但是,相对论的内分泌变化,包括抑制素剖面期间的营业额自发卵泡囊肿的奶牛,目前还不清楚。在本研究中,关系的营业额滤泡囊肿和变化,在周边血液浓度的孕酮( p ) ,雌二醇17 β -雌二醇( e2 ) ,促黄体生成素( lh ) ,卵泡刺激素( fsh )和抑制素进行了审议,哺乳奶牛。五奶牛确诊为滤泡囊肿(卵泡超过25毫米,直径在缺乏一个黄体)进行调查。其卵巢的动态监测,利用超声检查,并抽取血液样本采集于2 -或3 -天在全国各地的实验。那天,当卵泡注定要成为一个卵泡囊肿达到超过800毫米直径的定义是一个良好的开始,囊性卵泡波。 4个5头牛表现出类似的模式囊性卵泡变化和荷尔蒙概况。数据来自4头牛被用于分析之间的关系,成交囊性卵泡和激素概况。两个或三个新的囊性卵泡波发生在每个奶牛在试验期。平均直径的囊性卵泡多于25毫米13至15天之后开始的囊性卵泡波,并开始下降, 1至6天前开始的,随后囊性卵泡波。水平的雌二醇和抑制素呈下降趋势,为7至9天前开始了一个新的囊性卵泡波,并增加与此同时,与新的滤泡囊肿增长。水平的卵泡刺激素上升为1至3天前开始了一个新的囊性卵泡波。本研究阐明了关系卵泡刺激素和抑制素期间的营业额自发卵泡囊肿的奶牛,并发现它是非常类似以前的结果对奶牛。目前的结果表明,增加卵泡刺激素的分泌以下减少抑制素分泌引发的营业额囊性卵泡,在奶牛自发滤泡囊肿。
关键词:奶牛,雌二醇17 β -雌二醇( e2 ) ,卵泡囊肿,卵泡刺激素( fsh ) ,抑制素
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变化在Inhibin 、滤泡刺激的激素、Luteinizing 激素、孕酮和Estradiol-17 的周边集中上β 在囊状滤泡期间转交在奶牛与自发囊泡囊肿
Kazuhiro KENGAKU1)2)3), Tomomi TANAKA1)3) 和Hideo KAMOMAE1)3)
1) 兽医、东京大学农业和技术的部门
2) Seibu 临床中心, 千叶Prefectural 联盟农业相互援助协会
3) 兽医学团结的研究生院, 岐阜大学
摘要。几项研究澄清, 囊泡囊肿退化和由最近生长替换显现出成新囊泡囊肿没有排卵, 即,卵巢囊泡囊肿转交在母牛的滤泡。但是, 内分泌学的变动相对, 包括inhibin 外形在自发囊泡囊肿期间转交在奶牛, 是不明的。在本研究、关系在囊泡囊肿之间转交和变化中在孕酮上(p) 的周边血液集中, estradiol-17β (E2), luteinizing 的激素(LH), 滤泡刺激激素(FSH) 并且inhibin 被审查了在分泌乳汁奶牛。五头母牛被诊断与囊泡囊肿(超过直径25 毫米滤泡在没有语科库luteum 时) 被调查了。他们的卵巢动力学被监测了使用ultrasonography, 并且血样被收集了在2 或3 天间隔时间在实验过程中。天当滤泡命运决定成为囊泡囊肿到达了超过直径8 毫米被定义了当囊状囊泡波浪的开始。四5 头母牛陈列了囊状囊泡变动和激素外形的相似的样式。数据从4 头母牛被使用了为对关系的分析在囊状滤泡转交和激素外形之间。二或三新囊状囊泡波浪发生了在各头母牛在实验性期间。囊状滤泡的卑鄙直径是超过25 毫米13 到15 天在囊状囊泡波浪的开始, 和它开始减少1 到6 天在随后囊状囊泡波浪的开始之前之后。E2 和inhibin 的水平倾向于伴随地减少7 到9 天在新囊状囊泡波浪的开始之前和对增量以新囊泡囊肿成长。FSH 的水平上升了1 到3 天在新囊状囊泡波浪的开始之前。本研究澄清了关系在FSH 和inhibin 之间在自发囊泡囊肿期间转交在奶牛和发现它与早先结果是非常相似为母牛。当前结果建议, 在FSH 分泌物的增量跟随对inhibin 分泌物的减少触发囊状滤泡转交在母牛与自发囊泡囊肿。
主题词: 奶牛, Estradiol-17β (E2), 囊泡囊肿, 滤泡刺激激素(FSH), Inhibin

参考资料: 雅虎翻译

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月之下玄
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都是医学专业的,看不懂~~~
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