Question

毕业论文摘要翻译成英文，哪位高手帮帮忙，万分感激？

题目：有氧运动对（ApoE-/-）小鼠NO信号传导相关细胞因子的影响及机制初探
研究目的：本研究试图以ApoE-/-小鼠为研究对象，并以NO信号传导相关机制作为研究线索，以有氧运动作为主要的干预措施，对运动干预及动粥样硬化形成进行研究，试图在有氧运动与NO信号传导相关机制之间进行探索。

研究方法：采用10周龄C57BL/6J ApoE(-/-)AS小鼠48只，♂，SPF级，体重(18.24±0.60)g。随机分为安静组（对照组）、有氧运动组、给药组（普伐他汀钠片），每组16只。对ApoE-/-小鼠进行12周有氧运动后通过血清检测、HE染色胸主动脉切片观察其形态学变化，应用酶联免疫吸附测定（ELISA）、逆转录-多聚酶链式反应（RT-PCR）等实验技术分别检测血清中胆固醇(TC)、甘油三脂（TG）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、（一氧化氮）NO、内皮素（ET）、降钙素基因相关肽(CGRP)、（一氧化氮合酶）NOS，胸主动脉中（C反应蛋白）CRP，(两面神激酶)JAK, (信号传导及转录激活因子)STAT mRNA的表达水平。
研究结果：①有氧运动组，给药组（普伐他汀钠片）血脂成份中 TC，TG，LDL，HDL含量与对照组相比较具有统计学意义；其中TC，TG，LDL的检测结果显示运动组与给药组相比较无统计学意义；有氧运动组血清HDL含量均低于对照组，给药组（P<0.05）；对NO的检测结果显示运动组血清 NO 水平明显高于对照组且（P<0.01），高于给药组且（P<0.05）。②通过HE染色对ApoE-/-小鼠主动脉的形态学观察，结果显示有氧运动能明显减轻主动脉的斑块形成。③ELISA法检测血清中内皮素（ET）浓度以对照组最高，给药组、运动组随之降低，对照组与给药组，运动组比较差异具有显著统计学意义（p<0.01），运动组与给药组比较无统计学意义（p<0.05）。血清中降钙素(CGRP)的浓度以安静组最低，其中对照组与运动组、给药组比较差异具有显著统计学意义（p<0.01），而运动组与给药组比较差异具有统计学意义（p<0.05）。血清中一氧化氮合酶（NOS）的含量以运动组最高，给药组、对照组随之降低。其中运动组与给药组，对照组比较差异均具有统计学意义（p<0.01）。④RT-PCR法检测JAK mRNA表达对照组最高，给药组最低，其中运动组与给药组、对照组比较差异具有统计学意义（p<0.05），CRP mRNA表达以对照组最高，运动组与给药组的条带亮度无明显差异，但均弱于对照组；对照组分别与运动组，给药组相比较差异具有统计学意义（p<0.05）。STATmRNA表达以对照组最高，给药组次之，运动组最弱；运动组与对照组比较差异具有显著统计学意义（p<0.01），给药组与对照组比较差异具有统计学意义（p<0.05）
结论：①通过对各组ApoE-/-小鼠血清检测可以表明有氧运动及给药均能降低血脂成份，进而对缓解动脉粥样硬化（AS）形成产生干预作用。②通过HE染色对ApoE-/-小鼠胸主动脉的形态学观察，表明有氧运动干预能明显减弱主动脉的斑块形成。③通过对实验对象的血脂及NO相关细胞因子的实验结果比较分析，表明有氧运动与给药（普伐他汀钠片）均能从某种程度对ApoE-/-小鼠动脉粥样硬化的形成进行良性干预作用，但实验结果显示两者对相关因子干预程度不同。④实验表明有氧运动能提高血清中NO，NOS，CGPR 的含量，降低ET的含量，在胸主动脉mRNA表达方面，有氧运动能抑制CRP，STAT，JAK的表达。

Answer 1

aerobic exercise on ( ApoE - / - ) mice NO signal transduction related cytokine effects and mechanism ofObjective: This study attempted to ApoE - / - mice as the research object, and takes the NO signal transduction related mechanism as research clues, to aerobic exercise as the main intervention measures, to exercise intervention and atherosclerosis research, attempts in the aerobic exercise and NO signal transduction related mechanism between exploration.Research methods: by10 weeks of age C57BL / 6J of ApoE ( - / - ) mice", AS48, SPF, body weight (18.24 +0.60) g. Were randomly divided into control group (control group ), the exercise group, medication group ( pravastatin sodium tablets ),16 rats in each group. On ApoE - / - mice after12 week aerobic exercise by serum detection, HE staining of thoracic aorta were observed the morphological changes, the application of enzyme linked immunosorbent assay ( ELISA ), reverse transcriptase polymerase chain reaction ( RT-PCR ) and other experimental techniques were used to detect the level of serum cholesterol ( TC ), glycerin three greases ( TG ), high density lipoprotein ( HDL ), low density lipoprotein ( LDL ), NO ( nitric oxide ), endothelin ( ET ), calcitonin gene related peptide ( CGRP ), NOS ( nitric oxide synthase ), thoracic aorta ( C reactive protein ( CRP ), Janus kinase ( JAK ), signal transduction and activators of transcription ) STAT mRNA expression level.Research results: the aerobic exercise group, medication group ( pravastatin sodium tablets ) blood lipid components in TC, TG, LDL, HDL content compared with the control group had statistical significance; in which TC, TG, LDL test results showed that exercise group and drug group is not significant; aerobic exercise serum HDL content were lower than the control group, medication group ( P < 0.05); for NO detection results show that the exercise group serum NO levels were significantly higher than that in control group ( P < 0.01), and was higher than that of the drug group (P < 0.05) and. II by HE staining of ApoE - / - mice aortic morphology observation, results show that aerobic exercise can reduce aortic plaque formation. The ELISA method for the detection of serum endothelin ( ET ) concentration in the control group the highest, the drug group, the exercise group decreased, the control group and the group, the exercise group comparison difference has statistical significance ( P < 0.01), the exercise group and medication group had no statistical significance ( P < 0.05). Serum procalcitonin ( CGRP ) concentration to quiet group minimum, one control group and the exercise group, medication group with significant difference (P < 0.01), and exercise group and medication group with significant difference ( P < 0.05). Serum nitric oxide synthase ( NOS ) content in the exercise group the highest, the drug group, the control group decreased. The exercise group and drug group, contrast group compare difference to all have statistical significance ( P < 0.01). The RT-PCR method for the detection of JAK mRNA expression in the control group the highest, lowest drug group, wherein the exercise group and drug group, the control group with significant difference ( P < 0.05), CRP mRNA expression in control group the highest, the exercise group and drug group band brightness had no obvious difference, but are weaker than the control group control group respectively; and the exercise group, medication group with significant difference ( P < 0.05). The expression of STATmRNA in the control group, medication group, the exercise group the weakest; exercise group compared with the control group the difference is statistically significant ( P < 0.01), the treatment group and control group, with significant difference ( P < 0.05)Conclusion: through the various ApoE - / - mice serum detection can show that aerobic exercise and medication can reduce the blood lipid components, and then to alleviate atherosclerosis ( AS ) formation of intervention effect. II by HE staining of ApoE - / - mouse thoracic aorta morphological observations, suggests that aerobic exercise intervention can significantly weakened aortic plaque formation. The experiment object of lipids and NO related cytokine experimental results and comparison analysis, reveals that aerobic exercise and medication ( pravastatin sodium tablets ) can in some degree on ApoE - / - mice atherosclerosis formation are benign intervention effect, but the experimental results show that both the correlation factor intervention to different degrees. The experimental results show that aerobic exercise can increase the serum NO, NOS, CGPR content, lower the content of ET, mRNA expression in thoracic aorta, aerobic exercise can inhibit the CRP, STAT, JAK expression.

追问

这个不行啊，还是谢谢，请不要用GOOGLE等在翻译，错误较多，求高手。

Answer 2

翻译这种专业性的东西，真的很难。看都不想看。自己努力吧~~~~