Question

--the patient lokks much better .__what_ is it that has made him __what__he is today？

-- Perhaps the special medicine and his family's patient care.

A.What; thatB.That; thatC.What; whatD.That; what为什么选C？？

Answer 1

第一个what是特殊疑问词作主语
第二个what是引导宾语从句的连词，what he is today，他现在的样子，而且what在从句中充当he is后的表语
简化为：what has made him what he is today? is it that是强调句的基本结构词，当特殊疑问词what被强调时强调结构it is...that...要变为疑问语序what is it that...?

Answer 2

首先要理解整句话想要表达的意思：病人看上去好多了，是什么（即第一个what）让他康复成现在这个样子的？第二个what就代指今天这个康复了一些的状态。
其实文章看多了就有语感了。也不需要太计较语法，就会知道答案。

Answer 3

答句是个嵌入it is ... that...强调句的特殊疑问句。显然问者对于it is后的内容好奇，问句中充当句首主语的代词，that不符条件，排除。“使他成为今天这个样子”，that不能单独作为表语完整地表达出意思，而what作代词成为he is后的表语，what he is 即成为him的宾语补足语，使句子意思表达完整。希望回答可以帮到你 ^_^

Answer 4

是什么成就了今天的他？

what sb is，成为什么样的人