Question

紧急求助一段医学英文的翻译，不要机器翻译的，要准确一些，急用，谢谢

To reproduce different aspects of dilated cardiomyopathy, genetically engineered hamsters and mice have been developed with β-myosin heavy chain mutation, dystrophin and MyoD-gene (specific skeletal muscle transcription factor) deficiencies, FKBP-12 deficiency (binding protein involved in regulation of ryanodine receptor), Gαq overexpression, Gsαoverexpression, mutation in the desmin gene, null mutation of the cardiac α-actin gene, deficiency in dystrophin and utrophin, mutation of the sarcoglycan gene, knockout of the muscle LIM protein gene, and mitochondrial mutation.Mutation in the force-generating contractile apparatus (myosin heavy chain mutations) leads to hypertrophic cardiomyopathy, whereas mutation in the cytoskeleton is more prone to induce dilated cardiomyopathy. Engineered mouse lacking dystrophin and utrophin develops severe muscular dystrophies and cardiomyopathy, similar to humans with dystrophin deficiency.

Answer 1

下面是我的翻译：

为了重现扩张性心肌炎的不同生理效应，经过基因工程培育的仓鼠和家鼠被人为诱导了β肌球蛋白重链突变，肌营养不良蛋白和MyoD基因（尤其是骨骼肌转录因子的）表达或发育缺陷，FKBP-12缺失（与蛋白质结合并参与ryanodine受体的调控），Gαq基因高度表达，肌间线蛋白基因突变，心α肌动蛋白基因非编码区突变，肌营养不良蛋白和utrophin（不知道这是神马东西~汗~）缺失，sarcoglycan基因突变，肌肉LIM蛋白基因敲除，以及线粒体DNA突变。动力收缩装置的突变（也就是肌球蛋白重链突变）会导致肥厚性心肌炎，而细胞骨架的突变更容易引起扩张性心肌炎。经过基因工程设计的缺乏肌营养不良蛋白和utrophin的小鼠，和缺乏肌营养不良蛋白的人类一样，患上了严重的肌营养不良和心肌炎。

我就是学医的，文章对我有点挑战性，呵呵，几个术语和名词解释或翻译不到位的，见谅~