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血清透明质酸和层粘连蛋白检测在肝纤维化诊断中的价值摘要:透明质酸(HyaluronicAcid,HA)和层粘连蛋白(Laminin,LN)均是构成人体基质的主要成分,生理... 血清透明质酸和层粘连蛋白检测在肝纤维化诊断中的价值
摘要:透明质酸(Hyaluronic Acid,HA)和层粘连蛋白(Laminin,LN)均是构成人体基质的主要成分,生理情况下二者在血液中含量较少,但均具有重要的生物学意义。近年来研究证实,HA和LN水平与肝纤维化的活动水平及程度密切相关,为了进一步探讨HA和LN对肝纤维化的诊断价值,我们应用放射免疫分析方法(RIA),对120例各种肝病患者及50例正常对照者血清中的HA和LN含量进行了观察。结果显示各肝病组患者血清中HA和LN含量均高于正常对照组,尤以肝硬化和慢性活动性肝炎患者最为显著,HA和LN的变化与肝病的病变程度和肝纤维化活动度成密切正相关,同时测定HA和LN可显著提高阳性诊断率。
关键词 肝纤维化;透明质酸;层粘连蛋白
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淘之夭姚
2006-03-13 · TA获得超过711个赞
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The transparent quality of serum is sour to glue with layer to connect the egg white the examination in the liver fiber the 化 examine a patient the inside's value
Summary:The main composition, physiology circumstance that transparent quality is sour( Hyaluronic Acid, HA) glue with layer to connect the egg white( Laminin, LN) to all constitute the human body 基 the quality next two contain the deal less in the blood, but all have the importance's biology meaning.Study the movable level and degree that proof, HA is with the LN level and liver fiber 化 closely related in recent years, for further study the HA to diagnosis liver fiber 化 with the LN the value, our applicationing to project the immunity analysis the method( RIA), right 120 every kind of liver patient of examples and 50 normal collator of examples the HA in the serum contained with LN to measure to proceeds observational.Consequently show each liver disease the set the variety for getting serum inside HA with LN containing measuring all higher than normal matched control, particularly with cirrhosis with hepatitis of chronic movable sex getting most for showing the 著 , HA with LN and liverish pathological changes degree with the liver fiber 化 movable degree closely and related, measurese the HA to can show the 著 the exaltation the masculine gender the diagnosis the rate with LN at the same time.
Key phrase liver fiber 化 ;The transparent quality is sour;The layer glues to connect the egg white
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tarthiya
2006-03-13 · TA获得超过621个赞
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Blood serum hyaluric acid and level adhesion protein examination in liver fibrosis diagnosis value.
Abstract: Hyaluric acid (Hyaluronic Acid,HA) and level adhesion protein (Laminin,LN) is constitutes the human body matrix the principal constituent, in the physiological situation the two the content are few in the blood, but has the important biology significance. In recent years studied the confirmation, HA and the LN level and the liver fibrosis active level and the degree close correlation, in order to further discussed HA and LN to the liver fibrosis diagnosis value, we applied the emission immunity analysis method (RIA),has carried on the observation to 120 examples each kind of disease of the liver patient and in 50 examples normal collators blood serum HA and the LN content. The result showed in various diseases of the liver group patient blood serum HA and the LN content is higher than normal comparison group, especially is most remarkable by liver cirrhosis and the chronic activity hepatitis patient, HA and the LN change and the disease of the liver pathological change degree and liver fibrosis activity becomes closely is being connected, at the same time determines HA and LN may remarkably enhance masculine diagnosis leads.
Key word liver fibrosis; Hyaluric acid; Level adhesion protein
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百度网友12e1faffa
2006-03-13
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closely and related, measurese the HA to can show the 著 the exaltation the masculine gender the diagnosis the rate with LN at the same time.
Key phrase liver fiber 化 ;The transparent
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