Question

___you may have, you should gather your courage to face the challenge.

A however a serious problem
B what a serious problem
C however serious a problem
D what serious a problem

Answer 1

C however serious a problem
however是副词，后面直接跟形容词副词，最后再加上冠词和名词。
whatever则是个代词，只能指代名词和代词。例如，whatever problem you may have

句子意思：不论遇到多严重的问题，你都要鼓足勇气面对挑战。
相关however 和 whatever 的用法可以见百度文库。http://wenku.baidu.com/view/91a2541afad6195f312ba65f.html

Answer 2

C

Answer 3

c