Question

英语达人，帮忙翻译一段文章， 谢谢

3 讨论
在鼻咽癌研究中发现，相同临床分期患者其预后有差别，造成这种差异的原因可能是由于肿瘤的生物学行为不同所致，因此以某些生物学指标来早期诊断、预测鼻咽癌患者的复发和转移成为鼻咽癌的研究重点（5）。
HSP70作为分子伴侣，在维持细胞的正常形态及功能中起着重要作用,参与其他蛋白质的折叠、转运、合成等过程,与细胞内的其他肽类蛋白质结合,参与细胞的抗损伤、修复和热耐受过程,其在多种疾病过程中的重要作用已经被大量证据证实（6）。正常细胞中，HSP70表达受细胞周期调控,而肿瘤细胞中突变或异常蛋白质的存在可刺激HSP70的合成，使其呈现持续的高表达(6)HSP70的表达在影响细胞的凋亡和癌基因及肿瘤的发展中起着十分重要的作用（2、）。现已有令人信服的证据,支持EB病毒是鼻咽癌的致病因子,肯定参与鼻咽癌的多阶段、多因素发生过程（7）。本研究发现HSP70在鼻咽癌患者组织中的表达与血清EB病毒IgA/VCA滴度有相关性，HSP70在临床Ⅱ、Ⅲ期鼻咽癌患者组织中的表达阳性率为60.5%，其表达及含量与血清EB病毒IgA/VCA滴度呈正相关（P=0.001），可能提示鼻咽癌细胞中EB病毒随癌细胞增生加速而增多可能是患者IgA/VCA滴度升高的原因（8），有可能是EBV等因素刺激导致了HSP70的表达，亦可能与HSP70表达使EBV感染的肿瘤细胞得以大量增殖有关。已有研究认为HSP70-2 在鼻咽癌组织中表达与鼻咽癌发生危险度有关（9）。

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Answer 1

3 Discussion
Detection in the nose swallow the cancer research, homology clinical cent expect a sufferer to have difference after preparing, result in the reason of this kind of difference may be because of the biology behavior dissimilarity of tumor with the result that, so come to earlier period to diagnose by some biology index signs, estimate the nose swallow a cancer a sufferer to relapse and transfer to become a nose to swallow a cancerous research point.(5)
The HSP70 is a member companion, having already emphasized to want a function in normal appearance and function maintaining cell, participating other proteins to fold, transport, synthesize etc. process, combining with other 肽 proteins in the cell, anti- harm, repair and heat which participate cell bear to be subjected to process, it has already been confirmed by a great deal of proof in the important function in various disease processes.(6)Normally in the cell, HSP70 expressions are adjusted by cell period to control, but the mutation or the unusually protein existence in the tumor cell can stimulate HSP70 to synthesize, making it present keep on of high expression(6) HSP70 of the expression includes in the influence 凋亡 and cancer gene of the cell and the development of the tumor very important function.(2, )There has been the person of ream believing the proof of now, the support EB virus is a nose to swallow a cancer of with the result that cause of disease son, the affirmation participates a nose to swallow cancer of many stage, many factor occurrence process.(7)This research discovers the HSP70 is in the nose swallow the cancer the sufferer the organization of expression and the serum EB virus IgA/VCA drop degree have relativity, HSP70 the expression masculine gender rate presents for 60.5%, its expression and content and the serum EB virus IgA/VCA drop degree in the clinical Ⅱ , Ⅲ the period the nose swallow the cancer the sufferer the organization just related(P=0.001), possible hint nose's swallowing the EB virus in the cancer cell and increasing and living acceleration but increasing with the cancer cell may be sufferer IgA/VCA drop the degree go up of reason(8), probably is EBV etc. the factor incitement cause HSP70 of expression, may also can and HSP70's expressions make EBV infection of the tumor cell can propagate in great quantities relevant.There hasing been the research thinks HSP70-2 the expression and the nose swallows cancer occurrence a dangerous degree in the nose swallow the cancer organization relevant.(9)

Answer 2

3 discussions
Detection in the nose swallow the cancer research, homology clinical cent expect the sufferer to have difference after prepare, result in the reason of this kind of difference may be because of the biology behavior dissimilarity of tumor with the result that, so come to earlier period to diagnose by some biology index signs, estimate the nose swallow a cancer a relapse of sufferer and transfer to become a nose to swallow a cancerous research point.(5)
The HSP70 is a member companion, have already emphasized to want a function in normal appearance and function maintain cell and participate fold, transport, synthesizing of other proteinses etc. process, combine with other Mao proteins in the cell, anti- harm, repair and heat which participate cell bear to be subjected to process and it has already been confirm by a great deal of proof in the important function in various disease processes.(6)In the normal cell, HSP70 expressions are adjust by cell period to control, but mutate in the tumor cell or abnormality protein of the existence can stimulate synthesize of HSP70 and make it present keep on of high expression(6) HSP70 of the expression includes in the influence Diao Wu and cancer gene of the cell and the development of the tumor very important function.(2, )Have already made the person believe the proof of already now, the support EB virus is a nose to swallow a cancer of with the result that cause of disease son, affirmation participates a nose to swallow cancer of many stage, many factor occurrence process.(7)This research discovers that the HSP70 swallows a cancer a sufferer the IgA/VCA drop degree of the expression and the serum EB virus within organization to contain relativity in the nose, the HSP70 is in the clinical Ⅱ , Ⅲ the period the nose swallows a cancer a sufferer organization of the expression masculine gender rate presents for 60.5%, its expression and content and the serum EB virus IgA/VCA drop degree just related(P=0.001), probably hint that the nose swallows the EB virus in the cancer cell to increase to living acceleration but increase with the cancer cell may be the drop of sufferer IgA/VCA the degree go up of reason(8), probably is EBV etc. the factor incitement caused HSP70 of expression, may also can and HSP70's expressions make EBV infection of the tumor cell can in great quantities propagate relevant.There has been the research think HSP70-2 the expression and the nose swallows cancer occurrence a dangerous degree in the nose swallow the cancer organization relevant.(9)

Answer 3

3 discussion
In nasopharyngeal carcinoma found in a study of the same prognosis in patients with clinical stage a difference, the reason for this difference may be due to the biological behavior of tumors caused by different, and therefore certain biological indicators to the early diagnosis, prediction nasopharyngeal Cancer recurrence and metastasis in patients with a focus on nasopharyngeal carcinoma (5).
HSP70 as a molecular chaperone, in the maintenance of normal cell morphology and function play an important role in the folding of proteins involved in other, transshipment, synthesis and so on, and the other cell protein peptide combination of cells involved in the anti-injury, repair, and heat tolerance, in a variety of diseases important role in the process of substantial evidence has been confirmed (6). Normal cells, the expression of HSP70 in the regulation of cell cycle, and mutations in the tumor cells or the presence of abnormal protein HSP70 can stimulate the synthesis, it has sustained high expression (6) the impact of HSP70 expression and apoptosis in cancer gene and tumor development plays an important role in (2). Is now compelling evidence to support EB virus is the causative agent of nasopharyngeal carcinoma, nasopharyngeal carcinoma certainly participate in the multi-stage, multi-factor in the process (7). The study found that HSP70 in patients with nasopharyngeal carcinoma tissue and serum EB virus IgA / VCA titer relevant and HSP70 in the clinical stage Ⅱ, Ⅲ patients with nasopharyngeal carcinoma tissue positive rate of 60.5%, and its expression EB virus content and serum IgA / VCA titers were positively correlated (P = 0.001), might prompt EB virus in nasopharyngeal carcinoma cells with proliferative cells may be accelerated and more patients with IgA / VCA titer of the reasons for the increase (8), EBV may be factors led to stimulate the expression of HSP70 and HSP70 expression may be related to EBV infection in a large number of tumor cells to proliferation. Studies have shown that HSP70-2 in nasopharyngeal carcinoma and nasopharyngeal cancer risk in the (9).

Answer 4

3 discussion
In nasopharyngeal carcinoma found in a study of the same prognosis in patients with clinical stage a difference, the reason for this difference may be due to the biological behavior of tumors caused by different, and therefore certain biological indicators to the early diagnosis, prediction nasopharyngeal Cancer recurrence and metastasis in patients with a focus on nasopharyngeal carcinoma (5).
HSP70 as a molecular chaperone, in the maintenance of normal cell morphology and function play an important role in the folding of proteins involved in other, transshipment, synthesis and so on, and the other cell protein peptide combination of cells involved in the anti-injury, repair, and heat tolerance, in a variety of diseases important role in the process of substantial evidence has been confirmed (6). Normal cells, the expression of HSP70 in the regulation of cell cycle, and mutations in the tumor cells or the presence of abnormal protein HSP70 can stimulate the synthesis, it has sustained high expression (6) the impact of HSP70 expression and apoptosis in cancer gene and tumor development plays an important role in (2). Is now compelling evidence to support EB virus is the causative agent of nasopharyngeal carcinoma, nasopharyngeal carcinoma certainly participate in the multi-stage, multi-factor in the process (7). The study found that HSP70 in patients with nasopharyngeal carcinoma tissue and serum EB virus IgA / VCA titer relevant and HSP70 in the clinical stage Ⅱ, Ⅲ patients with nasopharyngeal carcinoma tissue positive rate of 60.5%, and its expression EB virus content and serum IgA / VCA titers were positively correlated (P = 0.001), might prompt EB virus in nasopharyngeal carcinoma cells with proliferative cells may be accelerated and more patients with IgA / VCA titer of the reasons for the increase (8), EBV may be factors led to stimulate the expression of HSP70 and HSP70 expression may be related to EBV infection in a large number of tumor cells to proliferation. Studies have shown that HSP70-2 in nasopharyngeal carcinoma and nasopharyngeal cancer risk in the (9).

Answer 5

太专业了啊。 不好意思帮你不到。