
谁能帮我翻译一下一段英文(医学类) 不要直接搬用在线翻译。。。要语句流畅。。。
大写字母不用翻译Onecentralmoleculeinvolvedincellgrowthisp70S6KwhichisregulatedbyboththeRas/PI...
大写字母不用翻译
One central molecule involved in cell growth is
p70S6K which is regulated by both the Ras/PI3K/PTEN/
Akt/mTOR and Ras/Raf/MEK/ERK pathways
The p70S6K gene is amplified in approximately 9% of primary
breast cancers and elevated levels of its mRNA transcripts
are found in about 41% of the tumors
It is known that some PTEN-deficient cells and tumors that
are purported to grow in response to activated Akt are
hypersensitive to mTOR inhibitors. p70S6K activity is
reduced by mTOR inhibitors in PTEN-deficient cells and
transgenic PTEN+/- mice 展开
One central molecule involved in cell growth is
p70S6K which is regulated by both the Ras/PI3K/PTEN/
Akt/mTOR and Ras/Raf/MEK/ERK pathways
The p70S6K gene is amplified in approximately 9% of primary
breast cancers and elevated levels of its mRNA transcripts
are found in about 41% of the tumors
It is known that some PTEN-deficient cells and tumors that
are purported to grow in response to activated Akt are
hypersensitive to mTOR inhibitors. p70S6K activity is
reduced by mTOR inhibitors in PTEN-deficient cells and
transgenic PTEN+/- mice 展开
2个回答
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一个在细胞里生长的中心微粒是P70S6K, 它是被Ras/PI3K/PTEN/Akt/mTOR 和 Ras/Raf/MEK/ERK 路径所管制。
P70S6K基因比原乳腺癌基因扩大约9%,并且发现它的mRNA转录提升水平约是肿瘤的41%
众所周知的一些缺陷PTEN细胞和肿瘤细胞的栽培是被说为激活蛋白质的,是对抑制mTOR高度灵敏的。
P70S6K活动是通过在PTEN缺陷细胞和PTEN转基因中的mTOR抑制因子所减低
P70S6K基因比原乳腺癌基因扩大约9%,并且发现它的mRNA转录提升水平约是肿瘤的41%
众所周知的一些缺陷PTEN细胞和肿瘤细胞的栽培是被说为激活蛋白质的,是对抑制mTOR高度灵敏的。
P70S6K活动是通过在PTEN缺陷细胞和PTEN转基因中的mTOR抑制因子所减低
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