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摘要:目的建立了一种HPLC方法用于硝苯地平片的含量测定。方法采用ODS柱,以甲醇-水(60:40)为流动相,流速为0.8ml/min,检测波长为235nm。结果硝苯地平...
摘要:目的建立了一种HPLC方法用于硝苯地平片的含量测定。方法采用ODS柱,以甲醇-水(60:40)为流动相,流速为0.8ml/min,检测波长为235nm。结果硝苯地平浓度在0.0125~0.4mg/ml范围内线性关系良好,相关系数r为0.9999。高、中、低3个浓度的平均回收率分别为101.66%、99.99%、99.23%;日内RSD为1.56%;日间RSD为0.79%。结论本法专属性强,灵敏度高,结果准确,快速简便。
关键词:HPLC;硝苯地平;含量测定
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关键词:HPLC;硝苯地平;含量测定
麻烦各位大神不要用谷歌、有道和金山词霸翻译来给我回答,因为这些是被老师禁止用的,麻烦语法好的大神来帮帮忙。我会提高奖赏的,谢谢!! 展开
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Abstract: Objective To establish a HPLC method for the content determination of nifedipine tablets. Methods ODS column, methanol-water (60:40) as mobile phase, the flow rate was 0.8ml/min, the detection wavelength was 235nm. Results the concentration of nifedipine in 0.0125~0.4mg/ml linear range, correlation coefficient r is 0.9999. The average recovery of high, low, 3 concentrations were 101.66%, 99.99%, 99.23%; RSD for 1.56% days; day RSD 0.79%. Conclusion the method is specific, sensitive, accurate, rapid and simple. Keywords: HPLC; nifedipine; Determination of content
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Abstract:Objective To establishaHPLCmethodforthecontent determinationofthenifedipine.ODS columnwith methanol - water(60:40)as the mobile phaseflow rate was0.8ml/min,thedetection wavelength was235nm.Nifedipineconcentrationintherangeof0.0125 ~ 0.4mg/mlgood linear relationship,thecorrelation coefficient r= 0.9999.High,medium and lowconcentrationaveragerecoverieswere101.66%, 99.99%,99.23%;day RSDwas 1.56%;day RSDwas 0.79%.Conclusion This method isexclusive,high sensitivity,accurate,fast and easy.Keywords: HPLC;nifedipineDetermination of content;
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