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急求英语大神翻译:[摘要]目的:研究超微粉碎对厚朴显微特性及有效成分溶出的影响,为厚朴超微粉体的粒径控制与应用提供试验依据。方法:通过测定厚朴普通粉和超微粉的粒径、细胞的...
急求英语大神翻译:
[摘要]目的:研究超微粉碎对厚朴显微特性及有效成分溶出的影响,为厚朴超微粉体的粒径控制与应用提供试验依据。方法:通过测定厚朴普通粉和超微粉的粒径、细胞的破壁率、粉体的形貌结构等显微特性和提取率以及体外溶出量,比较常规粉碎与超微粉碎对厚朴粉体的显微特性、提取效率及溶出度的差异。结果:厚朴超微粉在扫描电子显微镜下绝大多数为细胞碎片,很难见到普通粉中完整的细胞存在,细胞破壁率大大提高,提取率显著增大;各粒度超微粉体在人工胃液和人工肠液中有效成分的溶出度均高于普通粉,在蒸馏水中23Hz超微厚朴粉溶出度低。结论:适度的微粉化能促进厚朴有效成分的溶出,其溶出度还受到溶出介质的影响,超微粉碎技术应用于厚朴具有可行性。
[关键词]厚朴;超微粉碎;超微粉体;显微特性;破壁率;提取率;溶出度; 展开
[摘要]目的:研究超微粉碎对厚朴显微特性及有效成分溶出的影响,为厚朴超微粉体的粒径控制与应用提供试验依据。方法:通过测定厚朴普通粉和超微粉的粒径、细胞的破壁率、粉体的形貌结构等显微特性和提取率以及体外溶出量,比较常规粉碎与超微粉碎对厚朴粉体的显微特性、提取效率及溶出度的差异。结果:厚朴超微粉在扫描电子显微镜下绝大多数为细胞碎片,很难见到普通粉中完整的细胞存在,细胞破壁率大大提高,提取率显著增大;各粒度超微粉体在人工胃液和人工肠液中有效成分的溶出度均高于普通粉,在蒸馏水中23Hz超微厚朴粉溶出度低。结论:适度的微粉化能促进厚朴有效成分的溶出,其溶出度还受到溶出介质的影响,超微粉碎技术应用于厚朴具有可行性。
[关键词]厚朴;超微粉碎;超微粉体;显微特性;破壁率;提取率;溶出度; 展开
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Objective: To study the effects of ultramicro pulverization on microstructure characteristics and effective components of Magnolia Bark stripping, to provide the experimental basis for magnolia bark powder particle size control and application. Methods: the release of breaking through the determination of Magnolia officinalis powder and superfine powder particle size, the rate of cell, and powder morphology and microstructure characteristics and the rate of extraction and in vitro, compared to conventional grinding and Superfine Microstructure Characteristics, the magnolia bark powder extraction efficiency and the difference in the dissolution rate. Results: in the scanning electron microscope for the vast majority of cellular debris, ultra fine powder of Cortex Magnoliae officinalis, very difficult to see the existence of a complete cell powder, cell wall broken rate is greatly increased, the extraction rate increased significantly; the size of ultrafine powder in artificial gastric juice in the extraction of active components is higher than the ordinary powder, in distilled water 23Hz ultrafine powder of low stripping magnolia. Conclusion: moderate powder can promote the effective components of Magnolia Bark stripping, its solubility but also by the stripping effect of medium, ultrafine grinding technology applied in Magnolia officinalis is feasible.
Objective: To study the effects of ultramicro pulverization on microstructure characteristics and effective components of Magnolia Bark stripping, to provide the experimental basis for magnolia bark powder particle size control and application. Methods: the release of breaking through the determination of Magnolia officinalis powder and superfine powder particle size, the rate of cell, and powder morphology and microstructure characteristics and the rate of extraction and in vitro, compared to conventional grinding and Superfine Microstructure Characteristics, the magnolia bark powder extraction efficiency and the difference in the dissolution rate. Results: in the scanning electron microscope for the vast majority of cellular debris, ultra fine powder of Cortex Magnoliae officinalis, very difficult to see the existence of a complete cell powder, cell wall broken rate is greatly increased, the extraction rate increased significantly; the size of ultrafine powder in artificial gastric juice in the extraction of active components is higher than the ordinary powder, in distilled water 23Hz ultrafine powder of low stripping magnolia. Conclusion: moderate powder can promote the effective components of Magnolia Bark stripping, its solubility but also by the stripping effect of medium, ultrafine grinding technology applied in Magnolia officinalis is feasible.
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[关键词]厚朴;超微粉碎;超微粉体;显微特性;破壁率;提取率;溶出度
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