Question

求翻译（英译汉），一定高分追加奖励！

CT, perception threshold to innocuous cold; HPT, heat pain threshold; LTT, light-touch perception threshold; PPT, pressure pain threshold; WT, perception threshold to innocuous warmth; (CT + WT), sum of innocuous thermal thresholds. Statistically significant differences are indicated (a) between groups *P<0.05; **P<0.01; (b) between treatments tP<0.05; tfP<0.01; (c) between sides *P<0.05. With permission from Kosek & Ordeberg (2000a).
(P<0.05) and a tendency to increased sensitivity to heat pain (P = 0.054) before surgery. However, at the second examination after surgery, no significant differences in sensitivity of any kind were seen between patients and controls. Furthermore patients also had reduced PPTs on the contralateral side before surgery. This was also normalized following operation. Interestingly, the same type of sensory aberrations seen before surgery in these patients with hip OA have previously also been registered by my collaborator Eva Kosek in patients with fibromyalgia (Kosek et al 1996). However, these abnormalities have not been found in similar studies of patients with rheumatoid arthritis and with trapezius myalgia (LefBer et al 2002a,b).

It is known from several studies that patients with fibromyalgia have increased substance P-like activity (SPLI) in cerebrospinal fluid (CSF) (Vaeroy et al 1988). In earlier investigations we have also analysed CSF samples from 11 patients with painful hip or knee OA for SPLI and compared them to a group of nine pain-free controls and nine patients with rhizopathic pain from a herniated lumbar disc (Lindh et al 1997). The SPLI in CSF from the OA patients was increased in comparison to the controls (Fig. 4) but also in comparison to the patients with rhizopathic pain. As shown in Fig. 5 there was a correlation between SPLI and pain score as recorded pre-operatively, but the increased SPLI was less than that seen in patients with fibromyalgia (Russell et al 1994). The OA patients in the study were all candidates for surgical joint replacement and had another CSF sample 5 months after the operation. SPLI had decreased, but was still higher than in the controls.
Thus these findings suggest a gradual transition in OA from uncomplicated nociceptive pain to secondary sensory disturbances having similarities with findings in patients with fibromyalgia. An interesting question is of course when these disturbances are reversible; it is obvious that they were reversible in the studies above; however we all know that widespread pain for example in patients

Answer 1

CT表现，感觉阈值，以无害的冷战;转移酶，热痛阈值; LTT ，轻触摸感觉阈值;的PPT ，压力痛阈;重，感觉阈值，以无害的温暖; （ +小波变换的CT ） ，总和无害热阈值。统计显着性差异说明（一）群体之间*铁“ 0.05 ; ** P ” 0.01 ; （ b ）在处理茶多酚“ 0.05 ;全要素生产率” 0.01 ; （三）双方之间*铁“ 0.05 。经许可由Kosek ＆ Ordeberg （ 2000年） 。

（ P “ 0.05 ）和增加的趋势热疼痛的敏感性（ P值0.054 ）在手术前。但是，在第二次手术后检查，无明显差异的敏感性任何形式被视为病人和控制之间。此外患者也减少了PPTs关于对侧手术前。这也是归下列作业。有趣的是，同一类型的感觉像差手术前看到在这些患者髋关节炎先前也已注册了我的合作者伊娃Kosek治疗纤维肌痛（ Kosek等人1996年） 。但是，这些异常都没有发现类似的研究在类风湿关节炎患者与斜方肌肌痛（ LefBer等人2002年，二） 。

这是已知的一些研究，纤维肌痛患者有增加P物质样活性（ SPLI ）在脑脊液（ CSF ） （ Vaeroy等人1988 ） 。在早先进行的调查，我们也分析脑脊液标本11例痛苦的髋关节或膝关节骨关节炎的SPLI和他们相比，一组9疼痛无管制和9例rhizopathic疼痛从腰椎间盘突出（林德等人1997年） 。脑脊液中的SPLI关节炎患者的增加相比，对照组（图4 ） ，而且在比较rhizopathic患者疼痛。图所示。 5之间存在着相关性SPLI和疼痛评分记录术前，但增加SPLI低于看到患者的纤维肌痛（罗素等人1994 ） 。骨关节炎患者的研究中均候选人关节置换手术，并再次脑脊液样本5个月后的作业。 SPLI有所下降，但仍高于对照。

因此，这些结果表明逐步过渡在OA从简单的二次伤害性疼痛感觉障碍有相似的结果，患者的纤维。一个有趣的问题当然是当这些干扰是可逆的，这是显而易见的，他们的研究可逆以上，但是我们都知道，例如广泛疼痛患者

Answer 2

好强大