请各位英文高手帮忙翻译一下下面几段文字

我们同意专家的意见,题目已经改为“相互作用”,文中相关的用词也做了修改。大量的相关资料显示:近年来,对于药物与DNA的相互作用研究主要是针对结合模式的研究。由于小分子物质... 我们同意专家的意见,题目已经改为“相互作用”,文中相关的用词也做了修改。
大量的相关资料显示:近年来,对于药物与DNA的相互作用研究主要是针对结合模式的研究。由于小分子物质与DNA、蛋白质等大分子物质的结合位点的多样性与复杂性,目前还没有可能以详细的结构示意图的形式表示出来。今后,随着研究手段的进步,结合大量深入的研究,相信能更透彻地解析其相互作用。
根据专家的建议,已经对图一中的标注进行了修改。
格式方面的不妥,给读者带来的不便,深表歉意,已经根据要求将字体扩大并采用双倍行距。
本实验从微观的角度分析该药物的作用机制,其结合模式与其他的喹诺酮类药物有相同之处,但结合参数值大小不同。然而,大量相关研究文献显示,其他喹诺酮类药物的参数值大小与其已知的药理或毒理作用强弱并未呈现一定的相关性,如果在文中明确提出其对于药理、毒理作用大小的参考价值,可能会导致一定的片面性。为了能够证明其体内相关过程以及药理、毒理特性,还需要结合相关的动物实验,目前该新药的药理、毒理还处于研究阶段,是否具有相关性还有待进一步论证。
从图一中可以看出,由于是沟槽结合模式,紫外吸收光谱的减色效应不是十分明显,在约280nm处有一个等吸收点,图中显示并不十分清楚,我们已在文中的“紫外研究”章节进行了补充阐述。
希望大家不要敷衍了事,毕竟我也快倾出所有了
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風▎焱へ连城5a0
2009-05-08 · 超过22用户采纳过TA的回答
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We agree with expert, the topic has already changed into " interaction " ,The relevant word has made an amendment too in the article.
A large number of relevant materials reveal: In recent years, it is mainly to combining the studying of the mode to study in interaction to medicine and DNA. Because lighted variety and complexity in the combination location of macromolecules materials such as little member material and DNA, protein,etc., may not come out in form of the detailed structural sketch map yet at present. In the future, with studying the progress of the means, combine a large amount of deep research, believe that can analyze its interaction more thoroughly.
According to the expert's suggestion, have already revised marking in Fig. 1.
The form is improper, the inconvenience brought to reader, feel terribly sorry, has already as requested expanded the script and adopted the double row spacing.
This experiment analyzes the function mechanism of this medicine in terms of microcosmic, it has something in common to combine the mode and other quinoline promise ketone medicines, but combine parameter value of different size. But, a large number of relevant research documents reveal, the value size of parameter of other quinoline promise ketone medicines has not presented certain relevance instead of known pharmacology or toxicological function power, if propose it in the article to pharmacology, toxicological function size reference value clearly, may cause certain one-sidedness. In order to prove its relevant course and pharmacology, toxicological characteristic in the body, need to combine relevant animal experiments, pharmacology, toxicity of this new medicine are also at the stage of studying at present, whether relevance still remains to further prove.
Can be found out from Fig. 1, because the cannelure combines the mode, it is not very obvious that absorb the effect of losing lustre of the spectrum purply outside, there are one,etc. to absorb some about 280nm, reveal in the picture that is not very clear, we have been already in " study purply outside " The chapter has been supplemented and explained.
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花未棉
2009-05-07 · TA获得超过918个赞
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We agree with the views of experts, the subject has been changed to "interaction", the article also related to the modified terms.
A large number of relevant information: In recent years, for drug and DNA study of the interaction model for binding studies. Because of small molecules with DNA, proteins and other macromolecules of the binding site of the diversity and complexity, there is no detailed structure may be expressed by the diagram. The future, as advances in research tools, combined with a large number of in depth research, I believe that a more thorough analysis of their interaction.
According to experts, has been on the chart of a modified label.
The wrong format, the inconvenience to the readers, sorry, the font has been expanded in accordance with the requirements and the use of double-spaced.
This experiment from the point of view of the micro-mechanism of the drug, the combination of models and other quinolones have in common, but the combination of parameter values of different sizes. However, a large number of relevant research literature shows that other quinolones size of the parameter values and their known pharmacological or toxicological effect has not shown a strong or weak correlation, if the text clearly its pharmacology, toxicology the role of the size of the reference value, may result in certain one-sidedness. In order to be able to prove that the relevant process in vivo, as well as pharmacological, toxicological properties, but also require a combination of related animal experiments, at present the pharmacology of new drugs, toxicological study is still in the stage, whether there is correlation be further argued.
Figure 1 can be seen, as is the groove binding mode, UV absorption spectra of Hypochromic effect is not very clear, in some there is a 280nm absorption, etc., the map does not show very clearly that we have in the text of the "UV-study" chapters were added on.
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光明不二
2009-05-07 · 超过29用户采纳过TA的回答
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We agree to the expert's opinion, the topic has been changed to "interaction", the relevant terms have also been redone.
A number of related data shows: in recent years, with the DNA for drug interaction is mainly directed against the combination model of research. Due to the small molecules and DNA, protein binding sites of macromolecular substances of diversity and complexity, yet with detailed structure may be in the form of drawing. In the future, with the progress of research method, combining a thorough research, believe to be able to more thorough analysis of its interactions.
According to the expert proposal, had the mark for a change.
Format of readers with, and apologize for the inconvenience caused and has been expanded and according to the requirements will be adopted double-spaced font.
This experiment from the Angle of microscopic analysis of mechanism, the drug combination model and other quinolone have similarities, but with different size parameters. However, a lot of related literatures, other quinolone size parameters of the pharmacological or toxicological effect known or not, the present paper puts forward its clear if the pharmacology and toxicology effect size for the reference value, may cause some one-sided. In order to be able to prove its body related process and characteristics of pharmacology and toxicology, still need unifies the related of animal experiments, the drug toxicology is still in the pharmacology, relevance, whether still further.
One can see from the graph, and is due to the groove uv absorption spectra of the blue effect is not very obvious, 280nm in one place as shown in the absorption, is not very clear, we have in the research of "chapters" the uv supplement.
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