Question

抗癌新药的简介

Answer 1

依据美国药物生产和研发协会(The Pharmaceutical Research and Manufacturers of America, 简称PhRMA) 公布的资料显示，2008年全球正在临床研究中的抗癌新药有750多种。其中小分子抗癌药物大约400种（参见陈清奇编著的《抗癌新药研究指南》，科学出版社。 2009年出版）。
美国MedKoo Biosciences, Inc.正在建立全球第一个抗癌药库，该公司的抗癌新药分子库的名单如下。 该网页列出了这些药物分子的化学结构，化学名称，抗癌作用机制，和开发商，相关的参考文献。
2DG | A 007 | Abiraterone acetate | ABT 518 | ABT 751 | ABT 869 | ABT 888 | Acadesine | Acetylcysteine | AEE788 | AEZS-108 | Afimoxifene | Alanosine | ALS357 | Alvespimycin | Alvocidib | Amifostine | Amonafide dihydroclhoride | Amonafide maleate | Amrubicin | Anamorelin hydrochloride | Annamycin | ANX-510 | AP 5346 | Apaziquone | Aplidine | APO-866 | Aroplatin | ARRY 334543 | ARRY-142886 | Arzoxifene | AT 7519 | Atamestanum | Atiprimod | ATN 224 | ATN-161 | Atrasentan | AVE8062 | AVN 944 | Axitinib | AZD0530 | AZD1152 | anoxantrone.
Batabulin sodium | Becatecarin | Belinostat | Bendamustine | Beraprost | Berubicin | BIBW 2992 | Bleomycin | Bleomycin | BMS-599626 | BN 2629 | BN 83495 | Bosutinib | Brivanib alaninate | Brostallicin;.
Calcitriol | Canertinib | Canfosfamide | Carbendazim | Carfilzomib | Carmustine | Casopitant mesylate | CBP501 | CC 8490 | CDB-4124 | Cediranib | Celecoxib | Cemadotin | CEP 7055 | Cevipabulin fumarate | CF 101 | CGC 11047 | CHIR 258 | CHIR 265 | Cilengitide | Clodroni acid | Combretastatin A-4 phosphate | CP 547632 | CP-724714 | CRA-024781 | CT 2106.
Darinaparsin | Deforolimus | Degarelix | Diethylnorspermine 4HCl | Demethylpenclomedine | Denibulin | Dexmethylphenidate hydrochloride | DHA-paclitaxel | Diflomotecan | Dimesna | DJ 927 | DMXAA | Docosahexaenoic acid | Dutasteride.
E7080 | E7820 | E7974 | EC17 | EC 20 | EC 145 | Edatrexate | Edotecarin | Edotreotide | Efaproxira | Elacridar | Elagolix | Elesclomol | Elinafide | Elsamitrucin | Eltrombopag | Eniluracil | ENMD 1198 | Enzastaurin | Epothilone D | Eribulin mesylate | ES 285 | Etalocib | Ethonafide | Ethynylcytidine | Exatecan | Exherin | Ezatiostat hydrochloride.
Fludarabine | Forodesine | Gallium maltolate | Gimatecan | Glufosfamide | Gossypol | GPX100 | GPX150 | Hexyl 5-aminolevulinate | HKI 272 | HMN 176 | HMN 214.
Imexon | Imidazoacridone | Incyclinide | Indibulin | Indisulam | INNO 206 | INNO 406 | Iobenguane | Irofulven | Isatoribine | Ispinesib | Ixabepilone | Kahalalide F | Karenitecin | Ketamine | KOS 1584 | KRN 5500 | KRX-0402 | KRX-0601.
L 377202 | Lanreotide | Laromustine | Larotaxel | Lasofoxifene | Lestaurtinib | Levoleucovorin | Lomeguatrib | Lonafarnib | LR 103 | Lucanthone | LY 573636.
M40403 | MB 07133 | MDAM | 2-methoxyestradiol | MGCD 0103 | Midostaurin | Mifamurtide | Mifepristone | Milataxel | Miltefosine | MK-0457 | MK 0731 | MKC 1 | MLN8054 | Motexafin gadolinium | MP-470. | MPC-6827.
NAC | NBI 42902 | Nilotinib | NM-3 | Nolatrexed | Noscapine | NOV-002 | NPI 2358 | Obatoclax | Octreotide | Oleandrin | Omacetaxine mepesuccinate | ON 01910 | Ortataxel | OSI 930 | Ozarelix.
P2045 | Palifosfamide | Palonosetron | Pamidronic acid | Patupilone | PCI-24781 | Pelitinib | Pelitrexol | PEP 005 | Perifosine | Phenoxodiol | Picoplatin | Pipendoxifene | Pixantrone | Plerixafor | Plevitrexed | Plitidepsin | PM00104 | PM02734 | Pomalidomide | PPI 2458 | Pralatrexate | PX-12 | PX-478 | PX-866 | Pyroxamide.
Quarfloxin | Quinagolide | R547 | R1645 | R1668 | RC3095 | Relacatib | Retaspimycin | RH1 | Romidepsin | Ropidoxuridine | Roquinimex | Rosabulin | RP-101 | RTA 402 | Rubitecan.
Salinosporamide A | Sapacitabine | Satraplatin | Seliciclib | Semapimod | Seocalcitol | Silibinin | Simotaxel | SN-2310 | SNS 032 | SNS 595 | Sodium phenylbutyrate | Sodium stibogluconate | SPI-1620 | Squalamine lactate | SR 31747 | SU14813.
TAC-101 | Talabostat | Talampanel | Talaporfin sodium | Talotrexin Ammonium | Taltobulin | Tamibarotene | Tandutinib | Tanespimycin | Tarenflurbil | Tariquidar | TAS-102 | TAS-108 | Tasidotin hydrochloride | Tegafur | Telatinib | Temsirolimus | Terameprocol | Tesmilifene | Tetrandrine | Thymalfasin | Thymectacin | Tipifarnib | Tirapazamine | TL-310 | Trabectedin | Tretazicar | Tretinoin | Triapine | Triciribine | Trilostane | Troxacitabine | TSU-68 | TXD-258.
UCN-01 | Ukrain | Uracil | Uridine triacetate | Vandetanib | Vatalanib succinate | Verteporfin | Vincristine sulfate | Vincristine tartrate | Vinflunine | WX 671 | WX UK1 | Xaliproden | YM-155 | ZD4054 | ZK epothilone | Zosuquidar trihydrochloride.