Question

__you've got a chance,you might as well make full use of it.

这个地方为什么选Now that,Although也有尽管的意思啊？

Answer 1

now that 是既然的意思啊，尽管和它的意思是相反的

Answer 2

你自己想想：用尽管翻译得通顺吗？
很明显是既然的意思。