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PathophysiologyofpainPainisdefinedas“anunpleasantsensoryandemotionalexperienceofactua...
Pathophysiology of pain
Pain is defined as “an unpleasant sensory and emotional experience of actual or potential tissue damage or an experience expressed in such terms”.7 During the last 13th World Congress on Pain in Montreal (Canada) the delegates adopted a Declaration that Access to Pain Management is a Fundamental Human Right.8 Pain is classified into three different types:3, 9 inflammatory, neuropathic and dysfunctional pain. Although this kind of classification schematizes and facilitates our clinical approach to treating pain, there is a large interindividual variability in the response of analgesics when administered to patients. However, in recent years, predicting the response of patients to analgesics is possible with improved genetic and neurophysiological characterizations of patients and better understanding of the pharmacokinetic properties of the medications administered, such as local anesthetics during epidural infusion. 展开
Pain is defined as “an unpleasant sensory and emotional experience of actual or potential tissue damage or an experience expressed in such terms”.7 During the last 13th World Congress on Pain in Montreal (Canada) the delegates adopted a Declaration that Access to Pain Management is a Fundamental Human Right.8 Pain is classified into three different types:3, 9 inflammatory, neuropathic and dysfunctional pain. Although this kind of classification schematizes and facilitates our clinical approach to treating pain, there is a large interindividual variability in the response of analgesics when administered to patients. However, in recent years, predicting the response of patients to analgesics is possible with improved genetic and neurophysiological characterizations of patients and better understanding of the pharmacokinetic properties of the medications administered, such as local anesthetics during epidural infusion. 展开
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Pathophysiology of painPain is defined as “an unpleasant sensory and emotional experience of actual or potential tissue damage or an experience expressed in such terms”.
病理生理学的painPain被定义为“一种不愉快的感觉和情绪体验的实际或潜在的组织损伤或一个经验表达这样的条款”。
7 During the last 13th World Congress on Pain in Montreal (Canada) the delegates adopted a Declaration that Access to Pain Management is a Fundamental Human Right.8 Pain is classified into three different types:3, 9 inflammatory, neuropathic and dysfunctional pain.
7在过去13日世界大会在疼痛在蒙特利尔(加拿大)代表们通过一项宣言,访问疼痛管理是人类的一项基本权利8疼痛是分为三种不同类型:3、9、神经性疼痛和功能失调的炎症。
Although this kind of classification schematizes and facilitates our clinical approach to treating pain, there is a large interindividual variability in the response of analgesics when administered to patients.
虽然这种分类schematizes和促进我们的临床方法来治疗疼痛,有一个大的不同个体间的变异在响应进行治疗时的镇痛药。
However, in recent years, predicting the response of patients to analgesics is possible with improved genetic and neurophysiological characterizations of patients and better understanding of the pharmacokinetic properties of the medications administered, such as local anesthetics during epidural infusion.
然而,近年来,预测患者对镇痛药的反应是可能的和改进的遗传和神经生理学特征的病人和更好的理解动力学特性的药物管理,如局部麻醉剂在硬膜外注入。
病理生理学的painPain被定义为“一种不愉快的感觉和情绪体验的实际或潜在的组织损伤或一个经验表达这样的条款”。
7 During the last 13th World Congress on Pain in Montreal (Canada) the delegates adopted a Declaration that Access to Pain Management is a Fundamental Human Right.8 Pain is classified into three different types:3, 9 inflammatory, neuropathic and dysfunctional pain.
7在过去13日世界大会在疼痛在蒙特利尔(加拿大)代表们通过一项宣言,访问疼痛管理是人类的一项基本权利8疼痛是分为三种不同类型:3、9、神经性疼痛和功能失调的炎症。
Although this kind of classification schematizes and facilitates our clinical approach to treating pain, there is a large interindividual variability in the response of analgesics when administered to patients.
虽然这种分类schematizes和促进我们的临床方法来治疗疼痛,有一个大的不同个体间的变异在响应进行治疗时的镇痛药。
However, in recent years, predicting the response of patients to analgesics is possible with improved genetic and neurophysiological characterizations of patients and better understanding of the pharmacokinetic properties of the medications administered, such as local anesthetics during epidural infusion.
然而,近年来,预测患者对镇痛药的反应是可能的和改进的遗传和神经生理学特征的病人和更好的理解动力学特性的药物管理,如局部麻醉剂在硬膜外注入。
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病理生理学的painPain被定义为“一种不愉快的感觉和情绪体验的实际或潜在的组织损伤或一个经验表达这样的条款”。7在过去13日世界大会在疼痛在蒙特利尔(加拿大)代表们通过一项宣言,访问疼痛管理是人类的一项基本权利8疼痛是分为三种不同类型:3、9、神经性疼痛和功能失调的炎症。虽然这种分类schematizes和促进我们的临床方法来治疗疼痛,有一个大的不同个体间的变异在响应进行治疗时的镇痛药。然而,近年来,预测患者对镇痛药的反应是可能的和改进的遗传和神经生理学特征的病人和更好的理解的药物的药代动力学性质,如l管理
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病理生理疼痛
疼痛的定义是“一种不愉快的感觉和情绪体验的实际或潜在的组织损伤或体验表达这样的条款”。7在过去的第十三世界疼痛大会在蒙特利尔(加拿大)的代表们通过一项宣言,获得疼痛管理是一项基本人权。8疼痛分为三种类型9:3,炎症,神经性疼痛和功能失调。虽然这种分类模式化,有利于治疗疼痛的临床方法,有镇痛药物反应个体差异大的患者给药时。然而,近年来,预测患者对镇痛药的反应可能与改进的遗传特性和更好地了解患者的用药的药代动力学性质和神经生理学,如局部麻醉药硬膜外输注。
疼痛的定义是“一种不愉快的感觉和情绪体验的实际或潜在的组织损伤或体验表达这样的条款”。7在过去的第十三世界疼痛大会在蒙特利尔(加拿大)的代表们通过一项宣言,获得疼痛管理是一项基本人权。8疼痛分为三种类型9:3,炎症,神经性疼痛和功能失调。虽然这种分类模式化,有利于治疗疼痛的临床方法,有镇痛药物反应个体差异大的患者给药时。然而,近年来,预测患者对镇痛药的反应可能与改进的遗传特性和更好地了解患者的用药的药代动力学性质和神经生理学,如局部麻醉药硬膜外输注。
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[他们明显都是用翻译工具的好吗,翻译的跟狗一样~~]
病理生理学上的疼痛
疼痛被定义为“因为实际或潜在的组织损伤或用相关术语表达的一种不愉快的感觉和情绪”。在过去的在蒙特利尔(加拿大)举行的第十三届世界疼痛代表大会上,代表们通过一项宣言,获得疼痛管理是一项基本人权。
疼痛被分为三种不同类型:炎症,神经性疼痛,以及功能失调性的疼痛。虽然这种分类有模式化的好处,并且有利于我们的治疗疼痛的临床方法,但是当给病患镇痛药物时,个体差异仍然很显著(就是病人的反应会很不同)。
然而,近年来,预测患者对镇痛药的反应变得可行了,因为我们对病人的基因和神经心理学方面的特征更了解了,而且对药物的属性和特征也有了更好的理解,比如硬脑膜外注射时使用的局部麻醉药。
病理生理学上的疼痛
疼痛被定义为“因为实际或潜在的组织损伤或用相关术语表达的一种不愉快的感觉和情绪”。在过去的在蒙特利尔(加拿大)举行的第十三届世界疼痛代表大会上,代表们通过一项宣言,获得疼痛管理是一项基本人权。
疼痛被分为三种不同类型:炎症,神经性疼痛,以及功能失调性的疼痛。虽然这种分类有模式化的好处,并且有利于我们的治疗疼痛的临床方法,但是当给病患镇痛药物时,个体差异仍然很显著(就是病人的反应会很不同)。
然而,近年来,预测患者对镇痛药的反应变得可行了,因为我们对病人的基因和神经心理学方面的特征更了解了,而且对药物的属性和特征也有了更好的理解,比如硬脑膜外注射时使用的局部麻醉药。
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