求医学论文摘要翻译 手译 100
目的：通过动物实验研究，观察益肾汤联合贝那普利对5/6肾切除大鼠肾功能改善的疗效及减少TGF-β1在肾组织的表达等优势，并探讨益肾汤改善肾功能可能的作用机制。方法：1.选...
目的：
通过动物实验研究，观察益肾汤联合贝那普利对5/6肾切除大鼠肾功能改善的疗效及减少TGF-β1在肾组织的表达等优势，并探讨益肾汤改善肾功能可能的作用机制。
方法：
1.选取SPF级健康SD成年雄性大鼠50只做为研究对象，适应性饲养1周后,随机抽出10只作为假手术组（A组），剩余40只用 5/6 肾切除法造CRF模型。
2.造模成功后选取符合研究标准的大鼠32只进行分组，分为B组：模型组8只；C组：贝那普利组8只；D组：中药组8只；E组：益肾汤联合贝那普利组简称中西医结合组8只，加上A组共5组。
3. 造模成功后即开始给药，各组分别给予相应药物的水煎剂。
4. 实验结束后检测24小时尿蛋白定量及血BUN、Scr 、RBC、Hb，并进行肾组织学观察和肾组织中TGF-β1 表达检测。
结果：
1.一般情况：实验期间,假手术组大鼠表现机警,反应快,皮毛致密、整齐而有光泽,生长、进食及活动情况均无明显异常,体重增加；模型组明显营养不良,精神萎靡,活动迟缓,食欲不振,皮毛蓬松、枯槁无光泽，在治疗过程中死亡2只，考虑可能由于肾衰竭所致；贝那普利组大鼠精神较假手术组萎靡,活动慢,皮毛蓬松；中药组大鼠表现与贝那普利组类似；中西结合组大鼠与假手术组大鼠一般表现无太大差别,只是皮毛干燥无光。
2.对血中BUN、Scr的影响：贝那普利组、中药组、中西医结合组能明显降低BUN、Scr的水平，与模型组比较有显著性差异（P＜0.05），但仍高于假手术组；中西医结合组与中药组、贝那普利组比较有显著性差异（P＜0.05）；中药组和贝那普利组比较差异无统计学意义（P＞0.05）。
3.对血液学的影响：中药组和中西医结合组能明显升高血RBC、Hb，与模型组比较差别有统计学意义（P＜0.05），但两组之间比较差别无统计学意义（P＞0.05）；贝那普利组与模型组比较差别无统计学意义（P＞0.05）。
5.病理变化，接受肾大部切除术的大鼠均可见基质增生、肾小球硬化，但和模型组相比，用药组肾小球硬化程度明显较轻，其中以中西医结合组肾小球硬化程度为最轻；免疫组化结果显示用药组肾组织中 TGF-β1的表达均明显低于模型组（P＜0.05）, 且中西医结合组更能降低TGF-B1在肾组织中的表达，与中药组和贝那普利组比较差别有统计学意义（P＜0.05）。
结论：益肾汤通过益气健脾、活血化瘀、利湿泻浊，能降低CRF大鼠血BUN、Scr，改善贫血，降低蛋白尿，能有效降低5／6肾切除致CRF大鼠肾组织中TGF-β1 的表达，从而减少ECM 的积聚，减缓肾纤维化的发展，延缓CRF的进展。充分说明益肾汤具有良好的抗肾纤维化作用，而且联合贝那普利后疗效更佳。
PS：1.关于有些中医术语的肯定很难为大家 这部分可以跳过
2.系统最高只能悬赏100分 但是只要翻译的好 我会追加的
今天看到有两位朋友回答 很高兴哈 不过两位的翻译一模一样 可能是机器翻译的吧
我看了一下 因为机器翻译的不通顺 所以我才在title上写明求“手译”的~~ 感谢两位朋友的热心哈 不过我还是想要手译 至少要通顺~ 展开
通过动物实验研究，观察益肾汤联合贝那普利对5/6肾切除大鼠肾功能改善的疗效及减少TGF-β1在肾组织的表达等优势，并探讨益肾汤改善肾功能可能的作用机制。
方法：
1.选取SPF级健康SD成年雄性大鼠50只做为研究对象，适应性饲养1周后,随机抽出10只作为假手术组（A组），剩余40只用 5/6 肾切除法造CRF模型。
2.造模成功后选取符合研究标准的大鼠32只进行分组，分为B组：模型组8只；C组：贝那普利组8只；D组：中药组8只；E组：益肾汤联合贝那普利组简称中西医结合组8只，加上A组共5组。
3. 造模成功后即开始给药，各组分别给予相应药物的水煎剂。
4. 实验结束后检测24小时尿蛋白定量及血BUN、Scr 、RBC、Hb，并进行肾组织学观察和肾组织中TGF-β1 表达检测。
结果：
1.一般情况：实验期间,假手术组大鼠表现机警,反应快,皮毛致密、整齐而有光泽,生长、进食及活动情况均无明显异常,体重增加；模型组明显营养不良,精神萎靡,活动迟缓,食欲不振,皮毛蓬松、枯槁无光泽，在治疗过程中死亡2只，考虑可能由于肾衰竭所致；贝那普利组大鼠精神较假手术组萎靡,活动慢,皮毛蓬松；中药组大鼠表现与贝那普利组类似；中西结合组大鼠与假手术组大鼠一般表现无太大差别,只是皮毛干燥无光。
2.对血中BUN、Scr的影响：贝那普利组、中药组、中西医结合组能明显降低BUN、Scr的水平，与模型组比较有显著性差异（P＜0.05），但仍高于假手术组；中西医结合组与中药组、贝那普利组比较有显著性差异（P＜0.05）；中药组和贝那普利组比较差异无统计学意义（P＞0.05）。
3.对血液学的影响：中药组和中西医结合组能明显升高血RBC、Hb，与模型组比较差别有统计学意义（P＜0.05），但两组之间比较差别无统计学意义（P＞0.05）；贝那普利组与模型组比较差别无统计学意义（P＞0.05）。
5.病理变化，接受肾大部切除术的大鼠均可见基质增生、肾小球硬化，但和模型组相比，用药组肾小球硬化程度明显较轻，其中以中西医结合组肾小球硬化程度为最轻；免疫组化结果显示用药组肾组织中 TGF-β1的表达均明显低于模型组（P＜0.05）, 且中西医结合组更能降低TGF-B1在肾组织中的表达，与中药组和贝那普利组比较差别有统计学意义（P＜0.05）。
结论：益肾汤通过益气健脾、活血化瘀、利湿泻浊，能降低CRF大鼠血BUN、Scr，改善贫血，降低蛋白尿，能有效降低5／6肾切除致CRF大鼠肾组织中TGF-β1 的表达，从而减少ECM 的积聚，减缓肾纤维化的发展，延缓CRF的进展。充分说明益肾汤具有良好的抗肾纤维化作用，而且联合贝那普利后疗效更佳。
PS：1.关于有些中医术语的肯定很难为大家 这部分可以跳过
2.系统最高只能悬赏100分 但是只要翻译的好 我会追加的
今天看到有两位朋友回答 很高兴哈 不过两位的翻译一模一样 可能是机器翻译的吧
我看了一下 因为机器翻译的不通顺 所以我才在title上写明求“手译”的~~ 感谢两位朋友的热心哈 不过我还是想要手译 至少要通顺~ 展开
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Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action.
Methods：
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2.After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E group: beneficial United kidney soup benazepril group referred to as traditional Chinese and western medicine group 8, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1.The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity , loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; Chinese Medicines large mouse performance and a similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.
05), but still higher than sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference ( P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
4. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.
05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissues, with the Chinese medicine group and the benazepril group has statistically significant difference (P <0.05). Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF.
Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
Methods：
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2.After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E group: beneficial United kidney soup benazepril group referred to as traditional Chinese and western medicine group 8, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1.The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity , loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; Chinese Medicines large mouse performance and a similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.
05), but still higher than sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference ( P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
4. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.
05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissues, with the Chinese medicine group and the benazepril group has statistically significant difference (P <0.05). Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF.
Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
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Objective:
Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action.
Methods:
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2. After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E Group : Yishen Decoction United benazepril group referred to as traditional Chinese and western medicine group of eight, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1. The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity, loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; medicine the performance of rats with similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.05), but still high in sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference (P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
5. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissue Expression, and traditional Chinese medicine group and the benazepril group has statistically significant difference (P <0.05).
Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF. Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action.
Methods:
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2. After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E Group : Yishen Decoction United benazepril group referred to as traditional Chinese and western medicine group of eight, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1. The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity, loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; medicine the performance of rats with similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.05), but still high in sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference (P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
5. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissue Expression, and traditional Chinese medicine group and the benazepril group has statistically significant difference (P <0.05).
Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF. Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
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Objective:
Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action.
Methods:
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2. After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E Group : Yishen Decoction United benazepril group referred to as traditional Chinese and western medicine group of eight, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1. The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity, loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; medicine the performance of rats with similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.05), but still high in sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference (P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
5. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissue Expression, and traditional Chinese medicine group and the benazepril group has statistically significant difference (P <0.05).
Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF. Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action.
Methods:
1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model.
2. After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E Group : Yishen Decoction United benazepril group referred to as traditional Chinese and western medicine group of eight, together with the A Group of 5 Group.
3. Successful modeling start after delivery, the groups were given corresponding drugs decoction.
4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay.
Results:
1. The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity, loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; medicine the performance of rats with similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur.
2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <0.05), but still high in sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <0.05); Chinese medicine group and the benazepril group was no significant difference (P> 0.05).
3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <0.05), but the difference between the two groups was not significant (P> 0.05); benazepril group compared with the model group was no significant difference (P> 0.05).
5. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <0.05), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissue Expression, and traditional Chinese medicine group and the benazepril group has statistically significant difference (P <0.05).
Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF. Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
参考资料： SSSSSSS
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